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Fontolizumab (CAT#: TAB-041)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IFNG Recombinant Antibody (HuZAF) TAB-041 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IFNG. Fontolizumab (planned trade name HuZAF) is a humanized monoclonal antibody and an immunosuppressive drug for the treatment of auto-immune diseases like Crohn's disease.
  • Target
  • IFNG
  • Type
  • IgG1
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, IHC and most other immunological methods.
  • CAS
  • 326859-36-3
  • Trade name
  • huzaf
  • Specific Activity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human interferon g) (human-mouse monoclonal antibody g1-chain), disulfide with human-mouse monoclonal antibody light chain, dimer
  • Predicted N terminal
  • H chain: MEWSWIF; L chain: METDTII
  • Molecular Weight
  • 150000
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  • Function
  • cytokine activity; interferon-gamma receptor binding;
  • Synonyms
  • IFNG; interferon, gamma; interferon gamma; IFN-gamma; immune interferon; IFG; IFI;

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